WASHINGTON (Reuters) - In the biggest speech of his nearly 50 years in public life, Joe Biden will spell out his vision for the presidency on Thursday when he accepts the Democratic nomination to challenge Donald Trump in the Nov. 3 U.S. election. Biden’s speech on the fourth and last night of the Democratic National Convention will be a crowning moment in a long political career for the former U.S. senator and vice president, who fared poorly in two previous runs for the White House in 1988 and 2008. It will conclude a nominating convention that was held virtually amid the coronavirus pandemic, with the party’s biggest names, rising stars and even prominent Republicans lining up via video to support Biden and attest to the urgency of ending what they called Trump’s chaotic presidency. Biden’s vice presidential choice, Kamala Harris, the first Black woman and Asian American on a major presidential ticket, accepted her nomination on Wednesday and accused Trump of failed leadership tha …