“Dushman-e-Jaan” is the story of two sisters, Ramsha and Rubab, and a man who made an irredeemable mistake caused by his pride and anger that destroyed the life of Ramsha. Rubab makes the mistake of befriending the same man unaware of the fact that he is her biggest enemy.
Tooba Siddiqui as Ramsha is the eldest daughter of her family. She belongs to a middle-class background and works hard to support her family. She is a straight-forward and headstrong girl.
Mohib Mirza as Hatim belongs to an elite background. He is proud, arrogant, and does not believe in the concept of marriage. Hatim and Ramsha work at the same office.
Madiha Imam as Rubab is a simple, sweet, and innocent girl who loves her family a lot. She is very close to her sister, Ramsha.
